Purpose. To evaluate the histopathological condition of the pulp in teeth with different levels of chronic periodontitis in humans.\r\nMethods. Twenty-five single-root nondecayed teeth were divided into three groups as follows: group 1, clinical attachment level\r\n(CAL) 3 to 4mm and alveolar bone loss (BL) from 4 to 6mm without reaching the tooth apex; group 2, CAL = 5mm and\r\nBL > 6mmwithout reaching the tooth apex; group 3, CAL = 5mmand BL > 6mmup to the tooth apex.Histological analyses were\r\naccomplished after laboratorial processing. Results. The mean of CAL was 3.2 �± 0.7mm in group 1, 7.6 �± 2.0mm in group 2, and\r\n12.1�±2.8mmin group 3, while for BL it was 4.8�±0.9 mm, 7.6�±2.2 mm, and 11.9�±2.1 mm, respectively. Histopathological data in\r\nthe pulpal chambers were similar among the three groups showing normal aspects, and, the radicular pulps showed variable levels\r\nof reactive dentin, fibrosis, dystrophic mineralizations, atrophy, and mononuclear inflammatory infiltrate. Conclusions. Gradual\r\nprogression of the chronic periodontitis led to changes in the histopathological aspects of the radicular pulp with progressive\r\ninvolvement.
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